MDxHealth (MDXH.BR): Research Note January 19th

The authoritative Journal of Urology published data demonstrating the clinical potential of its urine-based epigenetic bladder cancer test AssureMDx™ to aid urologists in the management of patients presenting with haematuria. The study demonstrated the test's high negative predictive value (99.2%) for the detection of bladder cancer in this cohort of haematuria patients.

Oncosil Medical (OSL.AX): Initiating Coverage Report

Oncosil Medical (ASX:OSL) is an Australia based Life Sciences company that provides an innovative technology for safer and more effective radiation therapies for difficult to treat cancers like pancreatic cancer and hepatocellular carcinoma (HCC).  A CE Mark approval on its lead product Oncosil is imminent which will propel this company towards profitability.We believe the company is substantially undervalued.

Cellmid (ASX:CDY): Research Note

Cellmid Limited (ASX:CDY) is an Australian biotechnology company with a revenue generating consumer health division and a strong pipeline around a novel target,  midkine (MK), with applications in the treatment of cancer and inflammatory diseases. Cellmid has a fast growing consumer health division, which is generating increasing revenues from the Company’s proprietary FGF5 inhibitor hair growth products. . In 2015 the Company’s revenues increased by 63% to AUD 1.82 million and it is expected to generate close to AUD 4 million during the 2016 financial year from sales in Australia and Japan alone.

FINANCIAL INSTITUTE IN LIFE SCIENCES 

antonie van leeuwenhoek

(delft, netherlands 1632-1723):

founding father of modern biotechnology


We are proud our firm is named after one of the founding fathers of modern biotechnology: Antonie van Leeuwenhoek. Antonie van Leeuwenhoek was a Dutch scientist that lived in the 17th century: 'The Dutch Golden Age", a period in Dutch history, roughly spanning the 17th century, in which Dutch trade, science, military, and art were among the most acclaimed in the world. He was a Dutch tradesman and scientist and is commonly known as "the Father of Microbiology", and considered to be the first microbiologist.


He is best known for his work on the improvement of the microscope and for his contributions towards the establishment of microbiology. Using his handcrafted microscopes, he was the first to observe and describe single-celled organisms, which he originally referred to as animalculs,and which are now referred to as micro organisms. He was also the first to record microscopic observations of muscle fibers, bacteria, spermatozoa, and blood flow in capillaries (small blood vessels). Leeuwenhoek did not author any books; his discoveries came to light through correspondence with the Royal Society, which published his letters.




 


an unbiased and independent view on companies in the global life sciences sector


Van Leeuwenhoeck Institute (VLI) provides institutional investors and other professional investors with independent, un-biased research on the real value of innovative Life Sciences companies. Many institutional and individual investors will not invest in companies lacking independent third-party research coverage, yet few investment banks cover this sector because it requires dedicated expertise.


In spite of the lack of quality knowledge on an industry-wide basis, there is increased demand for life science-specific market research as investors are seeking information about leading companies in the sector in order to make well-informed investment decisions.

 


Resverlogix (RVX.TO): UPDATE Report May 2016

Resverlogix (RVX.TO) is a clinical stage cardiovascular company with an epigenetic platform technology that modulates protein production. In October 2015, Resverlogix initiated a Phase III trial ‘BETonMACE’ with apabetalone (RVX-208). The main objective of the Phase III BETonMACE trial will be to confirm MACE reduction in high risk cardiovascular disease patients with type 2 diabetes and low HDL. Based on our adjusted NPV valuation, we believe Resverlogix is substantially undervalued at the current share price of CAD 1.42. We have increased our valuation of Resverlogix to CAD 8.50 from CAD 5.85 per share. 

Phosphagenics (POH.AX)Initiating Coverage Report

Phosphagenics (ASX: POH) is an Australia based biotechnology company that is commercializing various products within the pharmaceutical, cosmetics and animal health sectors, using its proprietary drug delivery system called TPM® (Targeted Penetration Matrix). The lead products advancing through clinical trials are oxymorphone and oxycodone patches for the relief of various types of chronic pain. Based on our NPV valuation, we believe that Phosphagenics is substantially undervalued at the current share price and is trading heavily below cash. 

MDxHealth (MDXH.BR): Initiating Coverage Report

MDxHealth  is a market leader in the fast growing field of molecular testing focused on identification of DNA or RNA imprints, which can turn a healthy cell into a cancer cell. The main commercial focus of the Company is on urologic cancers, including prostate and bladder cancer, and it currently commercializes its proprietary ConfirmMDx® for Prostate Cancer test on the U.S. market and SelectMDx™ for Prostate Cancer on the European market. Using our valuation model the company’s current total value should be EUR 395 million, or EUR 8.72 per share

Invion Group (IVX.AX): UPDATE Report

Invion Group (ASX:IVX) is an Australian based biotech company focused on the development of treatments for large indications in respiratory disease and autoimmune disease.  In October 2015 Invion concluded its phase II program with oral INV102 in smoking cessation. The data showed that INV102 treated smokers were more likely to stop smoking completely or dramatically reduce the number of cigarettes smoked. The company expects an end of Phase II meeting with the FDA in the next few weeks to move INV102 into Phase III. 

Biofrontera (B8F.DE, B8F.L): Research Note

Biofrontera AG (B8F.DE, B8F.L) is a biopharmaceutical company specializing in the development of dermatological drugs. Its lead product is Ameluz®, a prescription drug approved for use in Europe for the treatment of mild to moderate actinic keratosis (AK) on the face and scalp in conjunction with photodynamic therapy (PDT). Recently, the company achieved a major milestone with the acceptance to file of the approval application for Ameluz® by the FDA in the US. Using our valuation model, the Company’s current total value is EUR 120-165 million, or EUR 5.00-7.00 per share.

MDxHealth (MDXH.BR): Research Note February 29th

Last week, MDxHealth’s share price went down with almost 20% due to a remark made by management of Exact Sciences (EXAS) during the publication of the 2015FY figures last Thursday. Management indicated that it has begun a program to replace Cologuard's NDRG4 biomarker, which is licensed to Exact Sciences by MDxHealth. EXAS expects this program will take 18 months to 24 months to complete. We find that the drop in share price is highly exaggerated